Intracytoplasmic sperm injection, or ICSI for short, is a procedure where your partner’s sperm is injected directly into your egg(s) for fertilization with IVF. You may have questions about using ICSI with IVF for male infertility and we are here to help. Here are some answers to common questions about ICSI.

The ICSI procedure can help you and your partner get pregnant despite certain male infertility problems, like the following:

  • Sperm unable to penetrate or fertilize an egg, low sperm count or poor sperm quality
  • A blockage or anatomical abnormality in the male’s reproductive tract that prevents him from producing or ejaculating sperm
  • Men who require a testicular or epididymal biopsy in order to conceive (such as after a vasectomy)

Why Use ICSI?
ICSI has been a tremendous benefit to IVF for over a decade and has revolutionized the treatment for couples that have severe male infertility. Know that even if there are no issues with your partner’s sperm, your doctor may still recommend ICSI with IVF. ICSI is often helpful even for couples that have not been successful with IVF in previous cycles.

Facts About ICSI
The ICSI procedure is becoming more common in IVF clinics because it virtually guarantees that the sperm penetrates the egg. In 2010 over half of all IVF cycles performed in the U.S. used ICSI. And, the vast majority (87 percent) of couples dealing with male factor infertility used ICSI with their IVF cycles.

With the ability to fertilize an egg with just one sperm, many infertile couples are finally becoming pregnant. If you’re dealing with male factor infertility or other fertility problems, talk to your doctor about the ICSI procedure.


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There are 5 steps to the ICSI process. The ICSI procedure is performed using a technique called micromanipulation. Click here to learn more.
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Learn more about potential risk factors and benefits associated with this treatment.
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Undergoing fertility treatment through ICSI will increase your chances of becoming pregnant! Learn more about success rates here.